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. 2022 Feb 21;13(2):167. doi: 10.1038/s41419-022-04561-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Flow chart for identifying and validating circRNAs in A549 cells. b Distribution map of circRNAs based on chromosome location. c Distribution map of circRNAs based on category. d Heatmap showing the top 15 most upregulated and top 15 most downregulated circRNAs in A549 cells treated with either 0, 2, or 4 Gy radiation, respectively. e Ten most representative circRNAs verified using RT-qPCR.