Why carry out this study?

Notwithstanding the fact that the care of hemophilia patients has improved dramatically over the last decade, some of them still experience joint bleeding.

Hemarthrosis is associated with acute pain and its recurrence leads to hemophilic arthropathy, which in turn leads to disability and chronic pain.

This review considers systemic and local pharmacological and non-pharmacological interventions for the management of acute and chronic pain in hemophilia.

What was learned from the study?

Acute and chronic pain in patients with hemophilia requires a multidisciplinary approach.

The management of pain due to hemophilic arthropathy still requires standardization. Meanwhile, the safest drugs should be used at the lowest effective dosage and for periods as short as possible.