Table 3.

In vitro and in vivo effects of bioactive compounds found in A. scoparia.

Compound	Metabolic Complications	Cardiovascular/dyslipidemia	Hepatic dysfunction	Cancer	Inflammation/oxidative stress	Neurological/Behavioral	Anti-microbial	Renal	Reproduction	Asthma/Allergy	Other
Coumarins
Scoparone	(132–136, 147)	(119, 122–134)	(137, 138, 140, 142, 154, 170–174)	(105, 164)	(149–151, 153–155, 157, 175, 176)	(126, 152, 161–163)	(165–167)	(136, 156)	(177)	(159, 160, 175)	(178) a (158, 179); b (169); c
Scopoletin	(108, 116, 180–190)	(126, 132, 191–199)	(154, 200–202)	(97, 203–213)	(114, 154, 214–245)	(106, 109, 110, 227, 246–264)	(165, 265–278)		(279)	(175, 251, 280–288)	(289, 290) d (291–293); b (294, 295); e (296–298); a
Esculetin	(116, 180, 299–312)	(303, 313–317)	(139, 171, 318–320)	(96, 321–349)	(226, 307, 318, 350–366)	(111, 367–372)	(165, 314, 373–375)	(107, 339, 376–378)	(379)	(282, 354, 380–383)	(384–386) b (387, 388); f (389); g
Flavonoids
Flavonols h	(57, 390–397)	(395, 398–402)	(395, 403, 404)	(395, 405, 406)	(395, 407)	(393, 395)	(395, 408)	(395)		(395)	(395, 409)
Rutin	(394, 397, 410–416)	(402, 417)	(412, 415, 418–421)	(422, 423)	(419, 420, 424, 425)			(418, 420)	(418, 420)	(417)	(421) d (412, 425); e
Flavanones i	(426–429)	(427, 430, 431)	(432)	(427, 433)	(427, 428, 434)		(435, 436)				(429) b (437); c
Chromones
Capillarisins	(116)		(438, 439)	(440–443)	(444–449)	(448)			(450)	(451)	(452) g
Phenolic Acids
Chlorogenic Acids j	(453–455)	(455–458)	(459)	(460, 461)	(71, 73, 222, 462–464)	(465–467)	(468–470)				(471) d
Prenylated coumaric acids k	(472–477)			(478–485)	(464, 472, 486–489)		(490, 491)			(492)	(493) d (488); e (494); l

^aMelanogenesis.

^bOsteoprotection.

^cRespiratory.

^dAging and healthspan.

^eGastrointestinal.

^fOphthalmic.

^gCartilage or muscle.

^hQuercetin and Isorhamnetin.

ⁱNaringenin and Blumeatin.

^jCaffeic acid, Dicaffeoylquinic acids, Chlorogenic acid.

^kArtepillins, Capillartemisins, Drupanin, Scopa-coumaricins.

^lHypoxia/ischemia.