TABLE 3.
Variables | Crude model |
Model 1 |
Model 2 |
Model 3 |
||||
OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | |
SHR1 Q1 (< 1.02) | Ref. | Ref. | Ref. | Ref. | ||||
SHR1 Q2 (1.02–1.15) | 0.838 (0.349–2.012) | 0.692 | 0.582 (0.222–1.527) | 0.272 | 0.708 (0.212–2.356) | 0.573 | 0.765 (0.224–2.611) | 0.669 |
SHR1 Q3 (1.15–1.44) | 0.902 (0.380–2.141) | 0.816 | 0.675 (0.268–1.699) | 0.404 | 1.096 (0.352–3.411) | 0.874 | 1.179 (0.366–3.795) | 0.782 |
SHR1 Q4 (> 1.44) | 2.921 (1.219–6.998) | 0.016 | 2.562 (0.994–6.599) | 0.051 | 2.789 (0.898–8.663) | 0.076 | 2.879 (0.903–9.184) | 0.074 |
SHR1 (> 1.35 vs. ≤ 1.35) | 3.000 (1.528–5.889) | 0.001 | 2.955 (1.427–6.116) | 0.004 | 2.922 (1.220–6.998) | 0.016 | 2.934 (1.198–7.189) | 0.019 |
SHR1 (per 0.1-point increase) | 1.179 (1.045–1.329) | 0.007 | 1.173 (1.019–1.337) | 0.017 | 1.200 (1.027–1.402) | 0.021 | 1.203 (1.026–1.411) | 0.023 |
SHR2 Q1 (< 0.79) | Ref. | Ref. | Ref. | Ref. | ||||
SHR2 Q2 (0.79–0.89) | 3.833 (1.169–12.567) | 0.027 | 3.012 (0.884–10.258) | 0.078 | 4.772 (1.035–21.994) | 0.045 | 5.311 (1.115–25.294) | 0.036 |
SHR2 Q3 (0.89–1.03) | 9.274 (2.938–29.276) | <0.001 | 8.168 (2.478–26.922) | 0.001 | 10.845 (2.377–49.479) | 0.002 | 13.609 (2.807–65.982) | 0.001 |
SHR2 Q4 (> 1.03) | 9.409 (2.844–31.134) | <0.001 | 8.201 (2.363–28.457) | 0.001 | 10.204 (2.134–48.784) | 0.004 | 16.976 (3.000–96.054) | 0.001 |
SHR2 (> 0.92 vs. ≤ 0.92) | 5.557 (2.897–10.657) | <0.001 | 5.475 (2.718–11.209) | <0.001 | 4.682 (1.997–10.977) | <0.001 | 6.325 (2.524–15.850) | <0.001 |
SHR2 (per 0.1-point increase) | 1.560 (1.260–1.932) | <0.001 | 1.576 (1.246–1.995) | <0.001 | 1.509 (1.145–1.987) | 0.003 | 1.770 (1.268–2.471) | 0.001 |
Model 1, adjusted for age and sex.
Model 2, adjusted for age, sex, current smoking, hyperlipidemia, atrial fibrillation, prior stroke, systolic blood pressure (SBP), and NIHSS at admission.
Model 3, adjusted for covariates from Model 2 and further adjusted for body mass index (BMI), diabetes, and triglyceride-glucose index (TyG).
In the sensitivity analysis, we adopted the previously established groups in Table 2 and excluded participants with top 5% SHR, bottom 5% SHR, or without lipid data.
SHR, stress hyperglycemia ratio.