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Possible ASD prevention method by modulating MIA with IL-17 related antibodies. Maternal psoriasis is one of the risk factors for offspring ASD. Three available antibodies against IL-17A or IL-17RA for psoriasis, psoriatic arthritis and ankylosing spondylitis could potentially be used for maternal patients. If the risk of ASD was reduced by clinical studies with these antibodies, the direct relationship between MIA and ASD through IL-17 signaling will clearly be revealed.
