Table 1.

Characteristic of the patients with T2DM and T2DM-GAN in the study.

Clinical parameters	T2DM	T2DM_GAN	p-value
Sex (male/female, n)	61/12	13/14	–
BMI (kg/m2)	27.13 ± 3.53	24.23 ± 3.18***	3.01×10−4
Age (year)	38.39 ± 4.01	53.44 ± 10.66***	7.56×10−8
ALT (U/L)	30.09 ± 19.28	25.52 ± 13.55	0.26
AST (U/L)	20.62 ± 9.01	24.67 ± 20.24	0.324
TBIL (μmol/L)	13.42 ± 4.57	11.03 ± 5.36*	0.029
DBIL (μmol/L)	4.20 ± 1.72	3.84 ± 1.95	0.378
UBIL (μmol/L)	9.26 ± 3.36	7.19 ± 3.83**	0.009
T_CHOL (mmol/L)	4.81 ± 1.39	4.36 ± 1.07	0.137
Triglyceride (mmol/L)	4.10 ± 4.04	1.91 ± 1.23***	5.21×10−5
HDL-C (mmol/L)	0.99 ± 0.69	0.99 ± 0.26	0.985
LDL-C (mmol/L)	2.61 ± 0.94	2.56 ± 0.81	0.779
FBG (mmol/L)	9.30 ± 3.77	8.20 ± 3.28	0.184
Fructosamine (mmol/L)	405.21 ± 107.28	371.96 ± 92.74	0.159
HbA1c (%)	10.13 ± 2.71	9.36 ± 1.92	0.178
BUN (mmol/L)	4.46 ± 1.11	5.35 ± 1.72**	0.003
Creatinine (μmol/L)	69.86 ± 14.07	65.93 ± 20.33	0.276
Uric acid (μmol/L)	366.72 ± 86.39	381.19 ± 105.91	0.486
WBC (109/L)	6.76 ± 1.41	6.12 ± 1.42*	0.049
Neutrophils (109/L)	3.68 ± 0.97	3.32 ± 1.26	0.143
Lymphocytes (109/L)	2.45 ± 0.70	2.22 ± 0.54	0.120
Monocytes (109/L)	0.42 ± 0.13	0.39 ± 0.10	0.328
Eosinophil (109/L)	0.17 ± 0.14	0.18 ± 0.19	0.940
Basophil (109/L)	0.03 ± 0.02	0.03 ± 0.02	0.635
RBC (1012/L)	5.13 ± 0.44	4.54 ± 0.46***	9.45×10-8
Hemoglobin (g/L)	156.73 ± 16.64	139.15 ± 15.13***	5.66×10-6
Hematocrit	0.46 ± 0.04	0.41 ± 0.04***	2.37×10-7
Platelets (109/L)	204.79 ± 54.23	205.00 ± 68.54	0.988
Plateletcrit	0.24 ± 0.05	0.23 ± 0.07	0.418

BMI, body mass index; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TBIL, total bilirubin; DBIL, direct bilirubin; UBIL, unconjugated bilirubin; T_CHOL, total cholesterol; HDL_C, high-density lipoprotein cholesterol; LDL_C, low-density lipoprotein cholesterol; FBG, fasting blood glucose; BUN, blood urea nitrogen; WBC, white blood cells; RBC, red blood cells

Data are presented as mean ± SD. P value is calculated using a two-tailed Student’s t test.

***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05.