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. 2022 Feb 22;77:103894. doi: 10.1016/j.ebiom.2022.103894

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© 2022 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig 1 — AAT levels in plasma of healthy donors and patients in ICU with SARS-CoV-2 or nsARDS.

a. Plasma AAT levels on first day of admission into ICU with SARS-CoV-2 (n = 11, 3.294 g/L+/-0.768) or nsARDS (2.923 g/L+/- 0.7984) as compared to healthy controls (n = 11) (1.73 g/L+/-0.104), P < 0.0001, P = 0.0013 respectively with no significant difference between SARS-CoV-2 and nsARDS at day 1. Significance was tested for by one way ANOVA with Tukey multiple comparison test (*p < 0.05). b. Plasma AAT levels in SARS-CoV-2 patients over the first 15 days of ICU admission (Mean: 3.2 g/L +/- 0.7 n = 20). c. Plasma alpha-1antitrypsin (AAT) levels in non-SARS-CoV-2 ARDS patients over the first 15 days of ICU admission (2.87 g/L +/-0.607) (n = 8).