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. 2022 Feb 22;77:103894. doi: 10.1016/j.ebiom.2022.103894

Figure 2.

Fig. 2.

Form and function of AAT in the plasma of SARS-COV-2 ARDS patients.

a. Western blot analysis for AAT in SARS-CoV-2 plasma from individual SARS-CoV-2 ARDS patients labelled P1,P2,P3 or P4 shows AAT at the appropriate molecular weight of 52 kDa without AAT-NE complexes or cleavage. b. FRET analysis demonstrate that AAT in the plasma of SARS-COV-2 patients is active and increased compared to healthy controls. P < 0.0001. Data represents mean AAT activity as the reciprocal of NE activity +/- SD. Significance was tested for by ANOVA; *p < 0.05.