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. 2022 Feb 4;20:925–936. doi: 10.1016/j.csbj.2022.01.016

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© 2022 Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 3 — Root mean square fluctuation (RMSF) and 2D principal component analysis (PCA) profiles pertaining to A. antagonist-bound A_2AR and B. agonist-bound A_2AR/mini-G $α$ _s. The regions that showed difference between without and with linker systems are indicated with green rectangles. The RMSF and 2D-(PCA) plots pertaining to 2nd replicate are given in SI Fig. 4.