Table 1.

Interview guide

Domain	Prompt
Reaction to VUS	What do you remember about receiving your genetic test results? How did you receive them? How did you feel about receiving your results (i.e. emotional reaction) What concerns or questions did you have about your results? What, if any information was missing? What do you think this result means for your future risk of getting colorectal cancer? Overall, how would you describe your experience with receiving your results?
Sharing VUS	Did you discuss or share your results with anyone? a healthcare provider? If so, who, when, and what did you discuss? a family member or friend? Without telling me any personal details about your familymember, can you describe who, when and what you discussed?
Perceived impact	Thinking back, what do you see as positives or negatives about having your genetic testing results returned to you? How have your results influenced your healthcare, if at all? How have your results influenced your day-to-day life, if at all? How have your results influenced the lives of family members, if at all?
Recommended improvements	If could do this process over again, would you choose to receive your results? Why,or why not? What went well about the process? (how notified, educational needs, provider support) What would you change to improve the process?