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. 2022 Jan 28;3(2):100508. doi: 10.1016/j.xcrm.2022.100508

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© 2022 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Temporal appearance and phenotype of infused populations within study subject peripheral blood NK cells

(A) The temporal appearance of infused populations within the study subject peripheral blood NK cells. Representative t-SNE analysis based on 19 markers of 1 study subject (P110) is shown. The numbers next to the gates represent the percentage of that population within total NK cells at the respective time point. Two populations with different kinetics of appearance are marked (the population on the top right is included in Figure 1C).

(B–E) (B and C) Comparison of the phenotypes. (D and E) The relative sizes of the infused NK cell populations detected in the circulation after infusion of the NK cell product for study subject P110 (B and D) and study subject P111 (C and E). The color coding in the t-SNE plots on the left represents the populations in the graphs to the right.