Table 3. Late Adverse Events of Patients by Treatment Group.
Adverse event | Events, No. (%) | P valuea | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Paclitaxel plus fluorouracil (n = 107) | Paclitaxel plus cisplatin (n = 107) | Paclitaxel plus carboplatin (n = 107) | ||||||||||||||
Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | ||
Cardiac | 9 (8.4) | 5 (4.7) | 0 | 0 | 0 | 9 (8.4) | 0 | 0 | 0 | 0 | 15 (14.0) | 1 (0.9) | 0 | 0 | 0 | .32 |
Esophagitis | 8 (7.5) | 5 (4.7) | 3 (2.8) | 1 (0.9) | 0 | 5 (4.7) | 2 (1.9) | 1 (0.9) | 0 | 0 | 3 (2.8) | 2 (1.9) | 1 (0.9) | 0 | 0 | .03 |
Pneumonitis | 33 (30.8) | 5 (4.7) | 0 | 0 | 0 | 29 (27.1) | 6 (5.6) | 0 | 0 | 0 | 32 (29.9) | 2 (1.9) | 1 (0.9) | 0 | 0 | .88 |
P values compared all grade late adverse events among 3 groups.