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. 2022 Feb 21;5(2):e220130. doi: 10.1001/jamanetworkopen.2022.0130

Table. Association Between Cancer Type and All-Cause Mortality Following COVID-19 Diagnosis Compared With Patients with Noncolorectal, Digestive Organ Cancer.

Cancer subtype (ICD-10 code) Mortality rate Patients, No. Univariate analysis Multivariate analysis, adjusted for age and sex Multivariate analysis, adjusted for age, sex, and comorbidities
With the cancer type With the cancer type who died OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
Myeloproliferative neoplasms and CML (C92.1, D45-D47) 0.529 17 9 1.87 (0.61-5.83) .30 2.04 (0.79-5.29) .14 2.00 (0.75-5.32) .16
Acute leukemia or MDS (C91.0, C92.0, D46) 0.506 89 45 1.70 (1.00-2.91) .04 2.11 (1.25-3.54) <.001 2.16 (1.30-3.60) <.001
Lung (C34) 0.494 265 131 1.63 (1.10-2.41) .01 1.63 (1.13-2.34) <.001 1.58 (1.11-2.25) .01
Myeloma/plasmacytoma (C.90) 0.493 134 66 1.62 (1.01-2.58) .04 1.53 (1.04-2.24) .03 1.53 (1.04-2.26) .03
Hematological cancer, other/unspecified 0.478 23 11 1.52 (0.58-3.99) .37 1.70 (0.66-4.42) .27 1.88 (0.72-4.94) .20
Urinary tract (C64-C68) 0.453 172 78 1.38 (0.89-2.14) .14 1.25 (0.77-2.01) .37 1.23 (0.76-1.97) .39
Prostate (C61) 0.43 272 117 1.26 (0.85-1.86) .26 0.72 (0.43-1.20) .20 0.69 (0.42-1.15) .16
Endocrine glands (C73-C75) 0.429 14 6 1.25 (0.34-4.29) .78 1.55 (0.39-6.18) .54 1.62 (0.39-6.71) .50
CNS (C69-C72) 0.404 52 21 1.13 (0.57-2.20) .75 1.63 (0.81-3.26) .17 1.66 (0.84-3.31) .15
CLL (C91.1) 0.397 68 27 1.10 (0.60-2.00) .77 1.04 (0.53-2.02) .91 1.07 (0.54-2.11) .84
Lymphomas (C81-C85, C88) 0.385 231 89 1.04 (0.69-1.57) .84 1.15 (0.73-1.81) .55 1.16 (0.74-1.84) .51
Other mature lymphoid leukemias (C96) 0.357 42 15 0.93 (0.43-1.94) .86 0.93 (0.48-1.79) .82 0.89 (0.45-1.74) .73
Mesothelial and soft tissue (C45-C49) 0.355 31 11 0.92 (0.37-2.14) >.99 0.96 (0.40-2.33) .93 0.96 (0.39-2.35) .93
Melanoma (C43-C44) 0.354 130 46 0.91 (0.56-1.48) .73 0.60 (0.36-1.00) .05 0.59 (0.35-1.00) .05
Colorectal (C18-C21) 0.34 253 86 0.86 (0.57-1.29) .49 0.84 (0.55-1.28) .42 0.84 (0.55-1.28) .41
Ill-defined (C76-C80) 0.304 23 7 0.73 (0.24-1.98) .65 0.62 (0.27-1.43) .27 0.67 (0.29-1.55) .35
Female genital organs (C51-C58) 0.299 107 32 0.71 (0.41-1.21) .21 1.43 (0.79-2.58) .24 1.45 (0.79-2.64) .23
Respiratory and intrathoracic organs (not lung; C30-C33, C35-C39) 0.278 18 5 0.64 (0.17-2.02) .46 0.73 (0.28-1.92) .52 0.72 (0.28-1.86) .50
Lip, oral cavity, and pharynx (C00-C14) 0.273 55 15 0.63 (0.30-1.25) .20 0.76 (0.38-1.51) .43 0.78 (0.39-1.54) .47
Breast (C50) 0.244 291 71 0.54 (0.36-0.81) <.001 0.80 (0.49-1.30) .37 0.85 (0.52-1.40) .53
Male genital organs, not prostate (C60, C62-C63) 0.133 15 2 0.26 (0.03-1.19) .09 0.40 (0.08-1.93) .26 0.40 (0.08-1.89) .25
Bone and articular cartilage (C40-C41) 0 6 0 0 (0-1.46) .09 0 (0 to ∞) NA 0 (0 to ∞) NA
Digestive organs, noncolorectal (C15-C17, C22-C26) 0.375 200 75 1 [Reference] NA 1 [Reference] NA 1 [Reference] NA

Abbreviations: CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; CNS, central nervous system; ICD-10, International Statistical Classification of Diseases and Related Health Problems, Tenth Revision; MDS, myelodysplastic syndrome; NA, not applicable; OR, odds ratio.