Table. Association Between Cancer Type and All-Cause Mortality Following COVID-19 Diagnosis Compared With Patients with Noncolorectal, Digestive Organ Cancer.
Cancer subtype (ICD-10 code) | Mortality rate | Patients, No. | Univariate analysis | Multivariate analysis, adjusted for age and sex | Multivariate analysis, adjusted for age, sex, and comorbidities | ||||
---|---|---|---|---|---|---|---|---|---|
With the cancer type | With the cancer type who died | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | ||
Myeloproliferative neoplasms and CML (C92.1, D45-D47) | 0.529 | 17 | 9 | 1.87 (0.61-5.83) | .30 | 2.04 (0.79-5.29) | .14 | 2.00 (0.75-5.32) | .16 |
Acute leukemia or MDS (C91.0, C92.0, D46) | 0.506 | 89 | 45 | 1.70 (1.00-2.91) | .04 | 2.11 (1.25-3.54) | <.001 | 2.16 (1.30-3.60) | <.001 |
Lung (C34) | 0.494 | 265 | 131 | 1.63 (1.10-2.41) | .01 | 1.63 (1.13-2.34) | <.001 | 1.58 (1.11-2.25) | .01 |
Myeloma/plasmacytoma (C.90) | 0.493 | 134 | 66 | 1.62 (1.01-2.58) | .04 | 1.53 (1.04-2.24) | .03 | 1.53 (1.04-2.26) | .03 |
Hematological cancer, other/unspecified | 0.478 | 23 | 11 | 1.52 (0.58-3.99) | .37 | 1.70 (0.66-4.42) | .27 | 1.88 (0.72-4.94) | .20 |
Urinary tract (C64-C68) | 0.453 | 172 | 78 | 1.38 (0.89-2.14) | .14 | 1.25 (0.77-2.01) | .37 | 1.23 (0.76-1.97) | .39 |
Prostate (C61) | 0.43 | 272 | 117 | 1.26 (0.85-1.86) | .26 | 0.72 (0.43-1.20) | .20 | 0.69 (0.42-1.15) | .16 |
Endocrine glands (C73-C75) | 0.429 | 14 | 6 | 1.25 (0.34-4.29) | .78 | 1.55 (0.39-6.18) | .54 | 1.62 (0.39-6.71) | .50 |
CNS (C69-C72) | 0.404 | 52 | 21 | 1.13 (0.57-2.20) | .75 | 1.63 (0.81-3.26) | .17 | 1.66 (0.84-3.31) | .15 |
CLL (C91.1) | 0.397 | 68 | 27 | 1.10 (0.60-2.00) | .77 | 1.04 (0.53-2.02) | .91 | 1.07 (0.54-2.11) | .84 |
Lymphomas (C81-C85, C88) | 0.385 | 231 | 89 | 1.04 (0.69-1.57) | .84 | 1.15 (0.73-1.81) | .55 | 1.16 (0.74-1.84) | .51 |
Other mature lymphoid leukemias (C96) | 0.357 | 42 | 15 | 0.93 (0.43-1.94) | .86 | 0.93 (0.48-1.79) | .82 | 0.89 (0.45-1.74) | .73 |
Mesothelial and soft tissue (C45-C49) | 0.355 | 31 | 11 | 0.92 (0.37-2.14) | >.99 | 0.96 (0.40-2.33) | .93 | 0.96 (0.39-2.35) | .93 |
Melanoma (C43-C44) | 0.354 | 130 | 46 | 0.91 (0.56-1.48) | .73 | 0.60 (0.36-1.00) | .05 | 0.59 (0.35-1.00) | .05 |
Colorectal (C18-C21) | 0.34 | 253 | 86 | 0.86 (0.57-1.29) | .49 | 0.84 (0.55-1.28) | .42 | 0.84 (0.55-1.28) | .41 |
Ill-defined (C76-C80) | 0.304 | 23 | 7 | 0.73 (0.24-1.98) | .65 | 0.62 (0.27-1.43) | .27 | 0.67 (0.29-1.55) | .35 |
Female genital organs (C51-C58) | 0.299 | 107 | 32 | 0.71 (0.41-1.21) | .21 | 1.43 (0.79-2.58) | .24 | 1.45 (0.79-2.64) | .23 |
Respiratory and intrathoracic organs (not lung; C30-C33, C35-C39) | 0.278 | 18 | 5 | 0.64 (0.17-2.02) | .46 | 0.73 (0.28-1.92) | .52 | 0.72 (0.28-1.86) | .50 |
Lip, oral cavity, and pharynx (C00-C14) | 0.273 | 55 | 15 | 0.63 (0.30-1.25) | .20 | 0.76 (0.38-1.51) | .43 | 0.78 (0.39-1.54) | .47 |
Breast (C50) | 0.244 | 291 | 71 | 0.54 (0.36-0.81) | <.001 | 0.80 (0.49-1.30) | .37 | 0.85 (0.52-1.40) | .53 |
Male genital organs, not prostate (C60, C62-C63) | 0.133 | 15 | 2 | 0.26 (0.03-1.19) | .09 | 0.40 (0.08-1.93) | .26 | 0.40 (0.08-1.89) | .25 |
Bone and articular cartilage (C40-C41) | 0 | 6 | 0 | 0 (0-1.46) | .09 | 0 (0 to ∞) | NA | 0 (0 to ∞) | NA |
Digestive organs, noncolorectal (C15-C17, C22-C26) | 0.375 | 200 | 75 | 1 [Reference] | NA | 1 [Reference] | NA | 1 [Reference] | NA |
Abbreviations: CLL, chronic lymphocytic leukemia; CML, chronic myeloid leukemia; CNS, central nervous system; ICD-10, International Statistical Classification of Diseases and Related Health Problems, Tenth Revision; MDS, myelodysplastic syndrome; NA, not applicable; OR, odds ratio.