Table III.
Univariate and multivariate survival analysis for ASPS patients after resection
| Variable (n, %) | Operative patients (n = 171) | Median OS (mon) (IQR) | 95% CI | P univariate | HR | 95% CI | P multivariate |
|---|---|---|---|---|---|---|---|
|
| |||||||
| Median age (IQR) | 27 (23, 37) | 0.98 | 0.95–1.0 | .341 | |||
| Sex | .067 | .884 | |||||
| Male | 79 (46.2) | 75.4 (42, NR) | 54–96 | Ref | - | ||
| Female | 92 (53.8) | 127.4 (74, NR) | 78–176 | 1.05 | 0.55–1.99 | ||
| Race | .075 | ||||||
| White | 109 (63.7) | 96.5 (48, NR) | 71–122 | Ref | - | - | |
| AA | 41 (23.9) | 74.3 (30, NR) | 60–89 | 0.858 | 0.41–1.80 | .687 | |
| Other | 21 (12.3) | NR | - | 0.540 | 0.16–1.82 | .321 | |
| Margin status | .003 | .413 | |||||
| Negative | 119 (69.6) | 127.4 (69, NR) | - | Ref | - | ||
| Positive | 34 (19.8) | 66.4 (21, NR) | 29–104 | 1.37 | 0.64–2.9 | ||
| Stage | <.001 | ≤.001 | |||||
| Localized | 99 (57.9) | NR | - | Ref | - | ||
| Metastatic | 72 (42.1) | 48.0 (22, 75) | 28–68 | 6.04 | 2.79–13.0 | ||
| Location | .894 | ||||||
| Trunk | 42 (24.6) | NR | - | ||||
| Extremity | 106 (62) | 96.5 (48, NR) | 66–127 | ||||
| H & N | 10 (5.8) | 77.7 (-) | 14–141 | ||||
| RP | 5 (2.9) | 76.8 (-) | - | ||||
| Tumor size (cm) | .007 | .536 | |||||
| >7.4 | 62 (36.3) | 76.8 (30, 127) | 58–95 | Ref | - | ||
| ≤7.4 | 90 (52.6) | NR | - | 1.23 | 0.64–2.35 | ||
| Extent of surgery | .211 | ||||||
| Local | 70 (40.9) | 77.7 (48, NR) | 56–99 | ||||
| Radical | 96 (56.1) | 107.4 (66, NR) | 69–146 | ||||
| Multimodal Rx | .008 | .340 | |||||
| No | 51 (29.8) | NR | - | Ref | - | ||
| Yes | 110 (64.3) | 75.4 (42, NR) | 71–80 | 1.47 | 0.66–3.28 | ||
| Facility type | .021 | .659 | |||||
| High volume | 150 (87.7) | 127.4 (47, NR) | 82–173 | Ref | - | ||
| Low volume | 21 (12.3) | 67.2 (54, 87) | 56–78 | 1.19 | 0.55–2.56 | ||
Patients with missing survival information are excluded. Bold indicates statistical significance.
AA, African American; H & N, head and neck; NR, not reached; RP, retroperitoneum.