Fig 6.

(A) Fluorescent AGEs, a product of non‐enzymatic glycation, accumulated nearly five times more in the diabetic group when compared to the WT controls. (B) CML, a product of glycoxidation normalized to the methylene peak (representative of type I collagen content), experienced significantly more accumulation in the diabetic MKR mice compared to the WT controls. (C) PEN, a fraction of the fluorescent AGEs present in bone, normalized to methylene (CH₂‐wag) accumulated at nearly double the amount of seen in the WT controls. CML = carboxymethyl‐lysine; PEN = pentosidine.