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. 2021 Feb 17;56(4):196–203. doi: 10.1136/bjsports-2020-103602

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Percent change in HR-pQCT measured bone variables, normalised to a 6-month mission. Individual data points are dichotomised by mission duration: x <6-month mission, o >6-month mission. Box plot depicting median and IQR is plotted next to individual data. HR-pQCT, high-resolution peripheral quantitative CT; F.Load, failure load; Tt.vBMD, total volumetric bone mineral density; Ct.vBMD, cortical vBMD; Tb.vBMD, trabecular vBMD; Tb.Th, trabecular thickness; Tb.N, trabecular number; Rad.D, dominant radius; Rad.ND, non-dominant radius; Tib.D, dominant tibia; Tib.ND, non-dominant tibia.