Table 1.
Patient 1 | Patient 2 | Patient 3 | |
---|---|---|---|
Hematological disease | IgM Κ WM | IgG Κ MM | IgG λ MM |
Age at diagnosis (years) | 67 | 86 | 72 |
Renal disease onset after hematological diagnosis (months) | 52 | 0 | 312 |
Renal function at diagnosis [GFR (MDRD; mL/min/1.72 m2)] | 55 | 60 | 83 |
Protein:creatinine ratio (mg/g) | 26 350 | 3565 | 1849 |
Urine monoclonal component (%) | 2.81 | 64.8 | 0 |
Serum monoclonal component (%) | 50.9 | 4 | – |
Serum albumin at renal disease diagnosis (g/dL) | 2.1 | 3.2 | 4.1 |
Nephrotic syndrome (yes/no) | Yes | Yes | No |
Renal pathology diagnosis | Podocytopathy | MCD | FSGS |
Renal replacement therapy | No | No | No |
Hematological remission | UT | UT | UT |
Renal remission | CR | PR | PR |
Renal replacement therapy | No | No | No |
Renal disease's specific treatment | Steroids | Steroids | No |
Other treatments | PEX | – | – |
CR: complete remission; PEX: plasmapheresis; PR: partial remission; UT: under treatment.