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. 2021 Nov 23;81(3):351–358. doi: 10.1136/annrheumdis-2021-221048

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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ACR and PASI response rates over time. (A) ACR20, (B) ACR50, (C) ACR70 and (D) PASI 90 response rates for RZB 150 mg and PBO over the 24-week, double-blind treatment period. PASI 90 results are among patients with ≥3% body surface area affected by psoriasis at baseline. *P≤0.05, **P≤0.01, ***P≤0.001. ^$Statistically significant under overall type I error control. ACR20/50/70, ≥20/50/70% improvement in American College of Rheumatology criteria score; PASI 90, ≥90% reduction in Psoriasis Area and Severity Index; PBO, placebo; RZB, risankizumab.