TABLE 1.

Susceptibilities of 200 S. pneumoniae isolates to 16 antimicrobial agents

Agent	MIC (μg/ml)			Isolate susceptibility (% of isolates)a
	Range	50%	90%	S	I	R
Penicillinb	<0.03–8	0.25	2	39.0	28.0	33.0
Cefotaxime	<0.03–16	0.5	2	61.5	16.5	22.0
Ceftriaxone	<0.03–32	0.5	2	61.5	15.5	23.0
Ceftazidime	<0.03–128	4	16
Cefepime	<0.03–8	0.5	2	57.5	18.5	24.0
Cefpirome	<0.03–8	0.12	1
Imipenem	<0.03–4	0.06	0.5	60.5	29.5	10.0
Meropenem	<0.03–4	0.12	0.5	61.5	28.5	10.0
Erythromycin	<0.03–>256	64	>256	18.0	5.5	76.5
Clarithromycin	<0.03–>256	128	>256	10.0	9.0	81.0
Ciprofloxacin	<0.03–4	1	2
Moxifloxacin	<0.03–0.5	0.12	0.25
Gentamicin	0.5–64	16	32
Rifampin	<0.03–0.25	0.06	0.12	100.0	0.0	0.0
TMP-SMZc	<0.12–>32	16	>32	13.0	6.0	81.0
Vancomycin	<0.03–1	0.25	0.5	100.0	0.0	0.0

^aS, susceptible; I, intermediate; R, resistant. 

^bAmong the 66 isolates for which MICs were ≥2 μg/ml, MICs were 2 μg/ml for 48 isolates, 4 μg/ml for 5 isolates, and 8 μg/ml for 13 isolates. 

^cRatio of concentrations of trimethoprim and sulfamethoxazole, 1:19.