TABLE 4.

Antimicrobial resistance and serogroup or serotype distributions of 200 S. pneumoniae isolates in specimens from different body sites

Specimen	No. of isolates	No. (%) of isolates nonsusceptiblea to the following:			No. (%) of each of the following major serogroups or serotypes:
		Penicillinb	Erythromycin	TMP-SMZ	23	19	6	14	3	9
Throat, nose, ear, or sinus	36	30 (83)	32 (89)	34 (94)	18 (50)	6 (17)	5 (14)	2 (6)	1 (3)	3 (8)
Sputum or bronchial washing	85	59 (69)	76 (89)	82 (96)	29 (34)	17 (20)	7 (8)	3 (4)	4 (5)	1 (1)
Blood	54	22 (41)	39 (72)	42 (78)	14 (26)	14 (26)	5 (9)	4 (7)	2 (4)	4 (7)
Cerebrospinal fluid	4	2 (59)	2 (50)	1 (50)	2 (50)	1 (25)	1 (25)	0 (0)	0 (0)	0 (0)
Pleural effusion	4	2 (50)	3 (75)	2 (50)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)	0 (0)
Miscellaneousc	17	7 (41)	12 (71)	13 (81)	2 (13)	6 (38)	3 (19)	2 (13)	3 (19)	1 (6)

^aIncludes intermediate and high-level resistant strains. 

^bThe numbers of isolates for which MICs were ≥2 μg/ml were as follows: 20 isolates from the throat, nose, ear, or sinus specimens, 30 isolates from sputum or bronchial washing specimens, 10 isolates from blood specimens, 2 isolates from cerebrospinal fluid specimens, 1 isolate from a pleural effusion specimens and 3 isolates from other specimens. Isolates for which penicillin MICs were 8 μg/ml were all recovered from respiratory sources. 

^cThese specimens included would discharge (14 isolates), ascites fluid (1 isolate), synovial fluid (1 isolate), and bile (1 isolate).