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. 2021 Sep 28;15(3):534–544. doi: 10.1093/ckj/sfab186

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© The Author(s) 2021. Published by Oxford University Press on behalf of the ERA.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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FIGURE 6: — Urinary mRNA levels of CCL5 and CXCL1 in different stages of glomerular lesion and renal interstitial fibrosis in DN group. (A) Periodic acid–Schiff staining of renal biopsy samples of DN. (B) Masson trichrome stain of renal biopsy samples of DN. (C) Urinary mRNA level of CCL5 in different stages of glomerular lesions according to Tervaert classification. (D) Urinary mRNA level of CCL5 in different degrees of renal interstitial fibrosis. (E) Urinary mRNA level of CXCL1 in different stages of glomerular lesions according to Tervaert classification. (F) Urinary mRNA level of CXCL1 in different degrees of renal interstitial fibrosis. Renal interstitial fibrosis was semi-quantitatively graded into mild (<25%), moderate (>25% but <50%) and severe (>50%). RIF: renal interstitial fibrosis. P < 0.05 was considered statistically significant.