Table 3.
Univariate Cox regression analysis for predictors of ESRD
| Variables | HR | 95% CI | P-value |
|---|---|---|---|
| Sex | 0.860 | 0.440–1.681 | 0.659 |
| Age (years) | 0.996 | 0.969–1.024 | 0.759 |
| T2DM duration (months) | 1.002 | 0.998–1.006 | 0.314 |
| Hb (g/L) | 0.977 | 0.961–0.993 | 0.004 |
| HbA1C (%) | 0.804 | 0.632–1.022 | 0.075 |
| Alb (g/L) | 0.953 | 0.905–1.004 | 0.068 |
| TC (mmol/L) | 0.989 | 0.816–1.199 | 0.912 |
| UA (umol/L) | 1.001 | 0.998–1.004 | 0.560 |
| eGFR (mL/min/1.73 m2) | 0.903 | 0.860–0.947 | <0.001 |
| uACR (mg/g) | 1.000 | 1.000–1.001 | <0.001 |
| Glomerulosclerosis (%) | 4.362 | 0.912–20.706 | 0.064 |
| Real interstitial fibrosis (%) | 40.725 | 12.155–136.451 | <0.001 |
| Relative urinary CCL5 mRNA | 1.461 | 1.233–1.732 | <0.001 |
| Relative urinary CXCL1 mRNA | 1.094 | 0.950–1.259 | 0.213 |
| Relative urinary CXCL6 mRNA | 1.365 | 0.824–2.260 | 0.226 |
| Relative urinary CXCL12 mRNA | 0.782 | 0.503–1.218 | 0.277 |
Hb: hemoglobin; HbA1C: glycosylated hemoglobin; Alb: albumin; TC: total cholesterol; UA: uric acid.