Table 1.
HIV-infected patients |
HIV-uninfected patients |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
HIV-TB | HIV-LTBI | HIV-Low TB risk | TOTAL | P | TB | LTBI recent | LTBI remote | Low TB risk | TOTAL | P | |
| |||||||||||
N | 32 | 45 | 90 | 167 | 170 | 76 | 34 | 18 | 298 | ||
Sex male, N (%) | 24 (75.0) | 39 (86.7) | 74 (82.2) | 137 (82.0) | 0.448* | 100 (58.8) | 37 (48.7) | 14 (41.2) | 8 (44.4) | 159 (53.4) | #0.148 |
Age, median (IQR) | 40 (32–51) | 36 (27–41) | 37 (29–49) | 37 (28–48) | 0.185§ | 37 (29–47) | 39(25–54) | 44 (32–56) | 39 (33–46) | 38 (28–49) | §0.461 |
BCG-vaccinated, N (%) | 23 (71.9) | 35 (77.8) | 19 (21.1) | 77 (46.1) | <0.001* | 116 (68.2) | 38 (50.0) | 15 (44.1) | 1 (5.5) | 170 (57.0) | #<0.001 |
TB diagnosis, N (%) | |||||||||||
Microbiological confirmation | 25 (78) | - | - | - | - | 132 (78) | - | - | - | - | |
Clinical diagnosis | 5(16) | - | - | - | - | 38 (22) | - | - | - | - | |
ART, N (%) | 18 (56.2) | 28 (62.2) | 27 (30.0) | 73 (43.7) | <0.001* | - | - | - | - | - | |
HIV RNA loglO copies/ml, median (IQR) | 4.91 | 1.84 | 4.65 | 4.47 | <0.001* | - | - | - | - | - | |
(3.60–5.41) | (1.59–4.29) | (3.92–5.26) | (2.22–5.18) | ||||||||
CD4 /mm3, Median (IQR) + | 124 (52–279) | 626 | 418 | 417 | <0.001* | - | - | - | - | - | |
(418–860) | (253 −631) | (208–646) | |||||||||
Origin, N (%) | <0.001* | *<0.001 | |||||||||
West Europe | 9 (28.1) | 10 (22.2) | 71 (78.9) | 90 (53.9) | 55 (32.3) | 39 (51.3) | 19 (55.9) | 18 (100) | 131 (44.0) | ||
East Europe | 7 (21.9) | 6 (13.3) | 7 (7.8) | 20 (12.0) | 65 (38.2) | 21 (27.6) | 8 (23.5) | 0 | 94 (31.5) | ||
Asia | 1 (3.1) | 2 (4.4) | 0 | 3 (1.8) | 23 (13.5) | 8 (10.5) | 2 (5.9) | 0 | 33 (11.1) | ||
Africa | 8 (25.0) | 7 (15.6) | 4 (4.4) | 19 (11.4) | 14 (8.4) | 5 (6.7) | 5 (14.7) | 0 | 24 (8.0) | ||
South America | 7 (21.9) | 20 (44.4) | 8 (8.9) | 35 (21.0) | 13 (7.6) | 3 (3.9) | 0(0) | 0 | 16 (5.4) |
TB: tuberculosis; BCG: Bacillus Calmette et Guérin; N: number; IQR: interquartile range.
Kruskal Wallis.
Fisher test.
Chi Square test.
CD4 count is not available for 5 patients (1 HIV-TB, 3 HIV-LTBI, 1 HIV-Low TB risk).