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. 2022 Feb 4;13:800986. doi: 10.3389/fphar.2022.800986

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Copyright © 2022 Mahmoud, Nabil, Hasan, El-Shazly, El-Ansari and Sobeh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Upper panel represents the effect of pretreatment with either pentagalloyl glucose (PGG) (100 or 200 mg/kg) or famotidine on gastric VEGF level of indomethacin-induced gastric injury. The lower panel represents densitometry analysis of the ratio of VEGF protein over β-actin protein. Data are expressed as mean ± SEM, n = 3. * and @ Statistically significant from control or indomethacin groups of rats, respectively, at p < 0.05 by one-way ANOVA was used for statistical analysis followed by Tukey’s post hoc test.