TABLE 6.
Comparison of HCMV antigenemia, viremia, and leukoDNAemia levels in HCMV-positive, NASBA-positive versus HCMV-positive, NASBA-negative blood samples from patients in group I (NASBA-positive patients) by type of transplant
HCMV assay | Transplant patient population | Median HCMV level (range) in HCMV-positive blood samples
|
Pa | |
---|---|---|---|---|
NASBA positive | NASBA negative | |||
Antigenemia quantitation | HTR | 16.0 (0–580) (n = 56) | 1.0 (0–38) (n = 43) | 0.0000 |
LTR | 10.0 (0–270) (n = 43) | 2.0 (0–27) (n = 41) | 0.0002 | |
BMTR | 8.0 (0–118) (n = 25) | 1.0 (0–25) (n = 38) | 0.0015 | |
Viremia quantitation | HTR | 0 (0–78) (n = 55) | 0 (0–8) (n = 43) | 0.0277 |
LTR | 0 (0–24) (n = 43) | 0 (0–5) (n = 41) | >0.05 | |
BMTR | 0 (0–40) (n = 24) | 0 (0–5) (n = 36) | >0.05 | |
LeukoDNAemia quantitation | HTR | 315.0 (10–10,000) (n = 55) | 65.0 (5–10,000) (n = 42) | 0.0002 |
LTR | 285.0 (5–7,900) (n = 43) | 85.0 (5–390) (n = 41) | 0.0002 | |
BMTR | 150.0 (5–6,940) (n = 25) | 17.5 (5–880) (n = 38) | 0.0124 |
Kolmogorov-Smirnov two-sample test.