TABLE 7.
NASBA result | No. of patients (median [range] antigenemia level) treated under guidance of
|
|||
---|---|---|---|---|
Antigenemia quantitation assay (actual treatment)
|
NASBA (predicted treatment)
|
|||
SOTRs with reactivations (n = 20) | BMTRs and SOTRs with primary infections (n = 19) | SOTRs with reactivations (n = 20) | BMTRs and SOTRs with primary infections (n = 19) | |
Positive | 8 (87 [3–580])a | 14 (13.5 [1–270])b | 15 (16 [0–124])c | 14 (9 [0–110])d |
Negative | 1 (1)e | 5 (2 [1–4])f | 0 | 0 |
Total | 9 | 19 | 15 | 14 |
Four patients started treatment because of a median antigenemia level of 158 (range, 124 to 580), and four started treatment because of a rejection episode with a median antigenemia level of 20.5 (range, 3 to 50).
Nine patients were BMTRs with a median antigenemia level of 18 (range, 4 to 105), and five were SOTRs with primary infections with a median antigenemia level of 9 (range, 1 to 270).
Upon NASBA positivity, the eight patients treated under antigenemia quantitation assay guidance had a median antigenemia level of 44.5 (range, 6 to 124), and the seven additional patients had a median antigenemia level of 5 (range, 0 to 38).
Upon NASBA positivity, among the same group of 14 patients treated under antigenemia quantitation assay guidance, the 9 BMTRs had a median antigenemia level of 11 (range, 1 to 110) and the 5 SOTRs with primary infections had a median antigenemia level of 7 (range, 0 to 100).
LTR treated because of rejection.
All BMTRs.