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. 1999 Apr;37(4):902–911. doi: 10.1128/jcm.37.4.902-911.1999

TABLE 7.

Actual antigenemia quantitation assay-guided treatment and predicted NASBA-guided treatment with respect to median antigenemia levels in the two major groups of differentially treated patients

NASBA result No. of patients (median [range] antigenemia level) treated under guidance of
Antigenemia quantitation assay (actual treatment)
NASBA (predicted treatment)
SOTRs with reactivations (n = 20) BMTRs and SOTRs with primary infections (n = 19) SOTRs with reactivations (n = 20) BMTRs and SOTRs with primary infections (n = 19)
Positive 8 (87 [3–580])a 14 (13.5 [1–270])b 15 (16 [0–124])c 14 (9 [0–110])d
Negative 1 (1)e 5 (2 [1–4])f 0 0
Total 9 19 15 14
a

Four patients started treatment because of a median antigenemia level of 158 (range, 124 to 580), and four started treatment because of a rejection episode with a median antigenemia level of 20.5 (range, 3 to 50). 

b

Nine patients were BMTRs with a median antigenemia level of 18 (range, 4 to 105), and five were SOTRs with primary infections with a median antigenemia level of 9 (range, 1 to 270). 

c

Upon NASBA positivity, the eight patients treated under antigenemia quantitation assay guidance had a median antigenemia level of 44.5 (range, 6 to 124), and the seven additional patients had a median antigenemia level of 5 (range, 0 to 38). 

d

Upon NASBA positivity, among the same group of 14 patients treated under antigenemia quantitation assay guidance, the 9 BMTRs had a median antigenemia level of 11 (range, 1 to 110) and the 5 SOTRs with primary infections had a median antigenemia level of 7 (range, 0 to 100). 

e

LTR treated because of rejection. 

f

All BMTRs.