Table 1.
Characteristics of studies investigating the effects of a single session of rTMS
| Study | n | Stroke | rTMS protocol | TMS measures |
|---|---|---|---|---|
| Takeuchi et al. (2005) | 10 | ≥ 6 mth | Contra-FDI, 90% rMT, 1 Hz, 1500 pulses | UH: MEP; iSP (UH → AH) |
| Kim et al. (2006) | 8 | > 3 mth | Ipsi-FDI, 80% rMT, trains of 20 pulses at 10 Hz, ITI of 68 s, 160 pulses; | AH: MEP |
| Talelli et al. (2007) | 6 | ≥ 1 year |
Ipsi-FDI, 80% aMT, iTBS, 600 pulses Contra-FDI, 80% aMT, cTBS, 600 pulses |
Bilateral: MEP; |
| Di Lazzaro et al. (2008) | 12 | ≤ 10 days |
Ipsi-FDI, 80% aMT, iTBS, 600 pulses Contra-FDI, 80% aMT, cTBS, 600 pulses |
Bilateral: rMT, aMT, MEP |
| Takeuchi et al. (2008) | 10 | ≥ 6 mth | Contra-FDI, 90% rMT, 1 Hz, 1500 pulses; | Bilateral: rMT; MEP; AH: SICI |
| Jayaram et al. (2009) | 9 | ≥ 11 mth | Contra-low limb, 120% aMT, 1 Hz, 600 pulses | Bilateral: MEP |
| Takeuchi et al. (2009) | 10 | > 6 mth | (Conta-sham + Ipsi-FDI, 90% rMT, 10 Hz, 50 pulses) × 20 | Bilateral: MEP; AH: SICI |
| Ackerley et al. (2010) | 10 | > 6 mth |
Ipsi-FDI, 90% aMT, iTBS, 600 pulses Contra-FDI, 90% aMT, cTBS, 600 pulses |
AH: MEP |
| Di Lazzaro et al. (2010) | 17 | < 10 days | Ipsi-FDI, 80% aMT, iTBS, 600 pulses | Bilateral: rMT, aMT, MEP |
| Takeuchi et al. (2012) | 9 | > 6 mth | Contra-FDI, 90% rMT, 1 Hz, 1200 pulses; | Bilateral: rMT, MEP; iSP (UH → AH), iSP (AH → UH) |
| Massie et al. (2013) | 8 | ≥ 6 mth | Ipsi-FDI/APB, 70% rMT, trains of 30 pulses at 3 Hz, ITI of 30 s, 900 pulses | AH: rMT, SICI, ICF |
| Massie et al. (2013) | 6 | ≥ 6 mth | Ipsi-FDI/APB, 70% rMT, trains of 30 pulses at 3 Hz, ITI of 30 s, 900 pulses | AH: SICI, ICF |
| Ackerley et al. (2014) | 13 | ≥ 6 mth |
Ipsi-FDI, 90% aMT, iTBS, 600 pulses Contra-FDI, 90% aMT, cTBS, 600 pulses |
Bilateral: MEP |
| Vongvaivanichakul et al. (2014) | 7 | > 6 mth | Contra-APB, 90% rMT, 1 Hz, 1200 pulses | UH: MEP |
| Cassidy et al. (2015) | 11 | ≥ 6 mth | Contra-Sham 6 Hz priming + Contra-1 Hz (FDI, 90% rMT, 1 Hz, 600 pulses) | AH: SICI, ICF, CSP; IHI (UH → AH), IHI ( AH → UH) |
| Goh et al. (2015) | 10 | > 6 mth | Ipsi-FDI, 90% r/aMT, trains of 50 pulses at 5 Hz, ITI of 30 s, 1200 pulses | AH: MEP |
| Tretriluxana et al. (2015) | 9 | > 6 mth | Contra-EDC, 90% rMT, 1 Hz, 1200 pulses | UH: MEP |
| Uhm et al. (2015) | 16, 6 | > 6 mth |
Ipsi-FDI, 90% rMT, trains of 50 pulses at 10 Hz, ITI of 55 s, 1000 pulses Ipsi-FDI, 110% rMT, trains of 50 pulses at 10 Hz, ITI of 55 s, 1000 pulses |
AH: MEP |
| Bashir et al. (2016) | 8 | > 6 mth | Contra-FDI, 90% rMT, 1 Hz, 1200 pulses | Bilateral: rMT, MEP, CSP, SICI, ICF |
| Di Lazzaro et al. (2016) | 15, 20 | < 10 days | Ipsi-FDI, 80% aMT, iTBS, 600 pulses | Bilateral: rMT, aMT, MEP |
| Murdoch et al. (2016) | 12 | ≥ 6 mth | Ipsi-FDI, 80% aMT, iTBS, 600 pulses | AH: MEP, SICI |
| Diekhoff-Krebs et al. (2017 | 14 | ≥ 12 mth | Ipsi-FDI, 80% aMT, iTBS, 600 pulses | Bilateral: MEP |
| Khan et al. (2017) | 15 | < 3 mth | Ipsi-FDI, 60% rMT, iTBS, 600 pulses | AH: rMT, MEP, CSP |
| Hanafi et al. (2018) | 8 | ≥ 6 mth |
Contra-FDI, 90% rMT, 1 Hz, 1200 pulses Ipsi-FDI, 80% rMT, trains of 50 pulses at 10 Hz, ITI of 25 s, 1000 pulses |
Bilateral: MEP |
| Tretriluxana et al. (2018) | 8 | 1—6 mth | Contra-EDC, 90% rMT, 1 Hz, 1200 pulses | UH: MEP |
TMS = transcranial magnetic stimulation, rTMS = repetative TMS, mth months, Contra contralesional, Ipsi ipsilesional, FDI first dorsal interosseous, UH unaffected hemisphere, AH affected hemisphere, MEP motor-evoked potential, iSP iplilateral slient period, ITI inter-train interval, iTBS intermittent theta burst stimulation, cTBS continuous theta burst stimulation, aMT, active motor threshold, rMT resting motor threshold, SICI short interval intracortical inhibition, APB abductorr pollicis brevis, ICF intracortical facilitation, CSP cortical slient period, IHI interhemisperic inhibition, EDC extensor digitorum communis