Correction to: PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/. BRCA1 DNA damage repair complex in prostate cancer cells

Correction to: J Exp Clin Cancer Res 37, 153 (2018)

https://doi.org/10.1186/s13046-018-0810-7

Following publication of the original article [1], the authors identified a minor error in Fig. 4; specifically:

• Fig. 4 b: Incorrect flow cytometry graphs of VEL (20uM) and SA + VEL were used; the figure has been corrected to use the correct graphs

Fig. 4.

Co-administration of SAHA and veliparib enhanced PCa cell apoptosis. PCa cells LNCaP, C4–2 and PC-3 were treated with SAHA and veliparib alone or in combination at the indicated doses for 4 days (a LNCaP. b C4–2. c PC-3. d VCap, CWR22Rv1, DU145). Cells were stained with FITC-Annexin V antibody and counterstained with PI. The apoptotic cells were analyzed by flow cytometery. Representative dot plots of FITC-Annexin V/PI staining are shown. Graph shows mean apoptotic cells (Annexin-V+/PI+) ± SD. Experiments were performed in triplicate. Cell apoptosis was validated by testing the protein levels of cleaved PARP by western blotting (a-d). *p < 0.05; ** p < 0.01 (SAHA or Veliparib alone vs. co-treatment)

The corrected figure is given here. The correction does not have any effect on the final conclusions of the paper.