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Genes and proteins related to osteogenesis and angiogenesis. A Fold increases of RUNX2, OCN and ALP genes. B Fold increases of HIF-1α, MMP-2, ROCK1 and VEGF genes. C Western blot of RUNX2, OCN and ALP proteins. D Western blot of HIF-1α, MMP-2, ROCK1 and VEGF proteins. All values were normalized to GAPDH. **P < 0.01, ***P < 0.001 and ****P < 0.0001 were obtained by comparison with uncoated Ti
