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. 2022 Feb 22;35(2):187–213. doi: 10.1007/s10534-022-00373-w

Table 1.

Metal binding affinities of proteins containing catalytic Zn2+ ions

Protein Kd (Zn2+)
Carbonic anhydrase

1 pM

(McCall and Fierke 2000)

Aminopeptidase B

0.37 pM

(Hirose et al. 2006)

Superoxide dismutase 1 (SOD1)

77 pM

(Crow et al. 1997)

Angiotensin-converting enzyme (ACE)

640 pM

(Schullek and Wilson 1988)

Sorbitol dehydrogenase

6 pM

(Krezel and Maret 2008)

Carboxypeptidase A

0.5 nM

(Williams 1960)

Dipeptidyl peptidase III (DPP III)

0.45 pM

(Fukasawa et al. 2011)

Glyoxalase I

27 pM

(Sellin and Mannervik 1984)

Matrix metalloproteinase-3 (MMP-3/stromelysin)

20 pM

(Maret 2004)