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. 2022 Jan 21;9(2):106–121. doi: 10.1002/acn3.51482

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© 2021 The Authors. Annals of Clinical and Translational Neurology published by Wiley Periodicals LLC on behalf of American Neurological Association

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Correlations between insoluble α‐syn (Syn1‐13G5B ELISA) and p‐α‐syn (pSyn/81A‐Syn1B ELISA) concentration measurements in LBD cases. We observed significant correlations (Spearman) between α‐syn and p‐α‐syn in all eight brain regions: (A) MFG, (B) ACG, (C) caudate, (D) IPL, (E) VAC, (F) precuneus, (G) hippocampus, (H) amygdala, with the strongest correlations (Spearman rho values > 0.9) in caudate, hippocampus, and amygdala. Data were corrected for multiple comparisons with the Holm‐Bonferroni method. ⁵² Lines were generated by linear regression.