Figure 5.

Comparison of insoluble α‐syn concentrations (Syn1‐13G5B) between LBD with measurable Aβ and LBD cases without measurable Aβ. The subgroup with Aβ accumulation had significantly higher α‐syn concentrations in ACG and amygdala, compared with the subgroup without measurable Aβ. Mean α‐syn levels were 18% higher in the PD with Aβ accumulation subgroup in the hippocampus and were 32%–73% in other regions. Data were analyzed with the two‐tailed Mann–Whitney test using a significance level of 0.05 and corrected for multiple comparisons with the Holm‐Bonferroni method. ⁵²