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. 2022 Feb 21;22:364. doi: 10.1186/s12889-022-12710-2

Table 3.

Study characteristics and association between anaemia or iron deficiency during postnatal period and mother–child interaction or bonding

Author & Year Study Design and Setting Risk of Bias Sample Size Assessment Tool Effect Measure and Significance
Murray-Kolb et al. 2009 [40] RCT double-blind, placebo; South Africa Low N = 95 (IDA-PL; 30, IDA-Fe; 34, and control; 31) Video recorder P = 0.007–0.032a
Perez et al. 2005 [41] RCT double-blind; South Africa Low N = 81 (IDA-PL; 21, IDA-Fe; 30 and Control; 30) Parent/Caregiver Involvement Scale P < 0.05
Hamm et al. 2020 [23] RCT open-label; USA Moderate N = 66 (single RBCs; 33, multiple RBCs; 33) Maternal Attachment Inventory 104 (102–104) vs 104 (102–104) p = 0.55b
Dearman et al. 2012 [42] Case–Control; England Moderate N = 115 (anaemic; 57, non-anaemic; 58) Postpartum Bonding Questionnaire P > 0.05

Key: aRanges in subscale analysis; maternal sensitivity (p = 0.032), structuring (p = 0.026), and non-hostility (p = 0.007)

bmedian score (range)