Table 1. Clinical data from the 49 EV-positive patients presenting with HFMD infections, Paraiba State, Northeastern region, Brazil, 2018.
| ID | Gender | Age | Signs and symptoms | Other findings | RT-qPCR qualitative result | Ct | Nested RT-PCR result | Species | EV genotyping by 5’UTR | Accession Number | EV genotyping by VP1 | Accession Number |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2B | Female | 1 year | Hand, foot and mouth lesions, fever | Body blisters | - | - | - | - | - | - | - | - |
| 3B | Male | 2 years | Hand, foot and mouth lesions | - | - | - | + | - | - | - | - | - |
| 4B | Male | 1 year | Hand and foot lesions | Buttocks lesions | + | 36.5 | + | EV-A | CV-A6* | MZ457015 | - | - |
| 5B | Male | 1 year | Trunk and limbs lesions, fever | - | - | - | + | EV-A | CV-A6* | MZ464040 | - | - |
| 6B | Female | 2 years | Hand, foot and mouth lesions | Body blisters | - | - | - | - | - | - | - | - |
| 7B | Female | 8 months | Hand, foot and mouth lesions | - | - | - | + | - | - | - | - | - |
| 8B | Male | 3 months | Hand, foot and mouth lesions | - | - | - | + | EV-A | CV-A6* | MZ464041 | - | - |
| 9B | Female | 10 months | Hand, foot and mouth lesions | - | + | 34.9 | - | - | - | - | - | - |
| 10B | Female | 1 year | Trunk and mouth lesions, fever | - | + | 30.4 | + | EV-A | Not assigned | MZ464042 | - | - |
| 11B | Male | 1 year | Hand, foot and mouth lesions, fever | Body blisters | - | - | - | - | - | - | - | - |
| 12B | Male | 1 year | Hand, foot and mouth lesions, fever | - | - | - | + | EV-A | CV-A6* | MZ464043 | - | - |
| 13B | Male | 1 year | Hand, foot and mouth lesions, fever | Seizure, blisters on the face and buttocks | + | 36.5 | + | EV-A | Not assigned | MZ464044 | - | - |
| 14B | Female | 5 years | Hand, foot and mouth lesions, fever | Buttocks lesions | + | 34.6 | + | EV-A | CV-A6* | MZ464045 | - | - |
| 15B | Male | 2 years | Hand, foot and mouth lesions, fever | Buttocks lesions, vomiting, body blisters | - | - | + | - | - | - | - | - |
| 16B | Male | 1 year | Hand, foot and mouth lesions | - | + | 37.8 | + | EV-A | Not assigned | MZ464046 | - | - |
| 17B | Male | 2 years | Hand, foot and mouth lesions, fever | Body blisters, diarrhea | + | 36.6 | + | EV-A | Not assigned | MZ464047 | - | - |
| 18B | Male | 1 year | Hand, foot and mouth lesions, fever | Body blisters | + | 34.1 | + | EV-A | Not assigned | MZ464048 | - | - |
| 19B | Male | 1 year | Hand, foot and mouth lesions, fever | Body blisters, buttocks and elbow lesions | + | 31.9 | + | EV-A | Not assigned | MZ464049 | - | - |
| 21B | Male | 4 months | Hand, foot and mouth lesions | Body blisters | + | 33.2 | + | EV-A | Not assigned | MZ464050 | - | - |
| 22B | Female | 1 year | Hand, foot and mouth lesions, fever | Body blisters | + | 31.5 | + | EV-A | Not assigned | MZ464051 | - | - |
| 23B | Male | 15 years | Hand and mouth lesions, fever | Body blisters | - | - | - | - | - | - | - | - |
| 24B | Male | 10 years | Hand, foot and mouth lesions | Body blisters | - | - | - | - | - | - | - | - |
| 25B | Female | 1 year | Hand, foot and mouth lesions, fever | - | + | 34.5 | + | EV-A | CV-A6* | MZ464052 | - | - |
| 26B | Male | 1 year | Hand, foot and mouth lesions | - | - | - | - | - | - | - | - | - |
| 27B | Male | 9 months | Hand, foot and mouth lesions, fever | Buttocks lesions | + | 29.8 | - | - | - | - | - | - |
| 28B | Male | 1 year | Hand, foot and mouth lesions, fever | - | + | 31.4 | - | - | - | - | - | - |
| 29B | Male | 8 months | Trunk and mouth lesions, fever | - | + | 33.8 | + | EV-A | CV-A6* | MZ464053 | - | - |
| 30B | Male | 1 year | Trunk and limbs lesions | Body blisters | - | - | + | EV-A | Not assigned | MZ476967 | - | - |
| 31B | Male | 1 year | Hand, foot and mouth lesions, fever | Body blisters | + | 30.7 | + | EV-A | CV-A6* | MZ476968 | - | - |
| 32B | Male | 1 year | Fever | Body blisters | - | - | - | - | - | - | - | - |
| 33B | Female | 2 years | Hand, foot and mouth lesions, fever | Perianal lesions | - | - | - | - | - | - | - | - |
| 34B | Male | 1 year | Hand, foot and mouth lesions, fever | - | - | - | - | - | - | - | - | - |
| 35B | Female | 1 year | Hand, foot and mouth lesions, fever | - | - | - | - | - | - | - | - | - |
| 36B | Male | 8 months | Hand, foot and mouth lesions, fever | Body blisters | + | 33.1 | + | EV-A | CV-A6* | MZ476969 | - | - |
| 37B | Male | 1 year | Upper and lower limbs lesions, fever | Buttocks lesions | - | - | - | - | - | - | - | - |
| 38B | Male | 1 year | Trunk and mouth lesions, fever | Vomiting | + | 26.0 | + | EV-A | Not assigned | MZ476970 | CV-A6 | MZ779206 |
| 39B | Female | 8 years | Trunk and limbs lesions | - | - | - | + | - | - | - | - | - |
| 40B | Male | 1 year | Hand, foot and mouth lesions | - | - | - | - | - | - | - | - | - |
| 41B | Female | 1 year | Trunk and mouth lesions, fever | - | + | 31.5 | + | - | - | - | CV-A6 | MZ779207 |
| 42B | Male | 1 year | Trunk and limbs lesions | Vomiting, diarrhea | - | - | + | - | - | - | - | - |
| 43B | Male | 1 year | Hand and foot lesions | Head lesions, coughing | - | - | + | - | - | - | - | - |
| 44B | Female | 3 years | Hand lesions, fever | Coughing | - | - | + | - | - | - | - | - |
| 45B | Female | 3 years | Trunk and limbs lesions | - | - | - | + | - | - | - | - | - |
| 46B | Male | 5 months | Trunk and limbs lesions | - | + | 33.4 | + | - | - | - | - | - |
| 47B | Male | 4 years | Trunk and limbs lesions | - | + | 35.4 | + | EV-A | Not assigned | MZ476971 | Not assigned | - |
| 48B | Female | 8 months | Trunk and limbs lesions | - | + | 28.0 | + | EV-A | Not assigned | MZ476972 | CV-A6 | MZ779208 |
| 49B | Male | 10 months | Trunk and limbs lesions | - | - | - | + | EV-A | CV-A6* | MZ476973 | - | - |
| 50B | Female | 1 year | Mouth lesions, fever | Enlarged ganglia | - | - | - | - | - | - | - | - |
*
According to the data obtained by the Enterovirus Genotyping Tool.