TABLE 5:
Sensitivity and Specificity for Grading Cartilage Lesions on Conventional MRI, qDESS, and qDESS Plus T2 Mapping Compared With the Arthroscopic Reference Standard
| Cartilage Lesion Grade, Sequence | Sensitivity (%) | Specificity (%) | Accuracy (%) | p a |
|---|---|---|---|---|
| 1 | ||||
| Conventional MRI | 33 (20–48) | 56 (51–60) | 53 (49–58) | NA |
| qDESS | 23 (12–37) | 53 (49–58) | 51 (46–55) | .81 |
| qDESS plus T2 mapping | 46 (31–61) | 39 (35–44) | 40 (35–45) | .80 |
| 2A | ||||
| Conventional MRI | 27 (18–37) | 53 (48–58) | 48 (44–53) | NA |
| qDESS | 26 (17–36) | 52 (47–56) | 47 (43–52) | .02 |
| qDESS plus T2 mapping | 58 (47–68) | 40 (35–45) | 43 (39–48) | < .001 |
| 2B | ||||
| Conventional MRI | 81 (71–88) | 64 (60–69) | 67 (63–71) | NA |
| qDESS | 76 (65–85) | 62 (57–67) | 65 (60–69) | .22 |
| qDESS plus T2 mapping | 86 (77–93) | 46 (41–51) | 53 (48–57) | .003 |
| 3 | ||||
| Conventional MRI | 93 (81–99) | 61 (57–66) | 64 (60–68) | NA |
| qDESS | 93 (81–99) | 60 (56–65) | 63 (59–67) | .45 |
| qDESS plus T2 mapping | 98 (88–99) | 44 (40–49) | 49 (44–53) | .63 |
Note—Values in parentheses are the 95% CI. qDESS = quantitative double-echo steady-state, NA = not applicable.
a
Values signify differences in the sensitivity and specificity confusion matrix between qDESS (with and without T2 maps for cartilage) and conventional MRI.