Table 1.
Marketed drugs for alleviating diabetic neuropathic pain (67).
| S. No. | Medication | Indication | Brand name | Company | Drug class |
|---|---|---|---|---|---|
| 1 | Pregabalin (systemic) | DPN | Lyrica | Pfizer | Gamma-aminobutyric acid analogs |
| 2 | Topiramate (systemic) | DPN | Topamax | Mylan | Carbonic anhydrase inhibitor (anticonvulsants) |
| 3 | Duloxetine (systemic) | DPN | Cymbalta | Eli Lilly | SNRIs |
| 4 | Capsaicin cream (topical) | DPN | Zostrix, Capzasin | – | Miscellaneous topical agents |
| 5 | Carbamazepine | Neuropathic pain | Tegretol | Novartis | Dibenzapine anticonvulsants |
| 6 | Gabapentin | Neuropathic pain | Neurontin | Pfizer | Gamma-aminobutyric acid analogs |
| 7 | Nortriptyline hydrochloride or desipramine hydrochloride) | Chronic pain | Pamelor | Mallinckrodt Pharmaceuticals | Tricyclic antidepressants |
| 8 | Venlafaxine ER | DPN | Effexor | Pfizer | SNRIs |
DPN, diabetic peripheral neuropathy; SNRI, serotonin–norepinephrine reuptake inhibitor.