. Author manuscript; available in PMC: 2022 Feb 22.

Published in final edited form as: Alzheimer Dis Assoc Disord. 2021 Apr-Jun;35(2):99–105. doi: 10.1097/WAD.0000000000000436

Table 2.

Linear regression estimating the association of mid-life cardiovascular risk factors and late-life cognition, KHANDLE Wave 1 (2017–2018).

	Executive Function	Semantic Memory	Verbal Episodic Memory	Global Cognition
Hypertension (ref= no)	−0.18 (−0.29, −0.06)	−0.11 (−0.22, −0.001)	−0.19 (−0.32, −0.07)	−0.19 (−0.30, −0.08)
Hyperlipidemia (ref=no)	−0.15 (−0.26, −0.03)	−0.11 (−0.23, 0.001)	−0.16 (−0.28, −0.03)	−0.18 (−0.29, −0.06)
BMI>25 (ref: BMI<25)	−0.15 (−0.26, −0.04)	−0.14 (−0.25, −0.04)	−0.23 (−0.34, −0.11)	−0.21 (−0.31, −0.11)
CVRF
0 CVRF	Ref	Ref	Ref	Ref
1 CVRF	−0.15 (−0.25, −0.04)	−0.16 (−0.26, −0.05)	−0.15 (−0.26, −0.03)	−0.18 (−0.28, −0.08)
2 CVRF	−0.26 (−0.39, −0.13)	−0.20 (−0.33, −0.07)	−0.34 (−0.48, −0.20)	−0.33 (−0.45, −0.21)

All models adjusted for age at KHANDLE, age at MHC, gender, race/ethnicity, participant education and parental education. Cognitive domain scores were z-standardized to the full KHANDLE Wave 1 sample (mean=0; SD=1).