FIGURE 3.

Noninvasive measurements of cerebral metabolic rate (CMRO₂, top left), OEF (top right), THC (bottom left), and [HbO₂] (bottom right). Lines indicate mean values, and the shaded area indicates the interquartile range. % baseline refers to the relative values compared with precooling, baseline values for animals. Note the stabilization of OEF and CMRO₂ in all non-DHCA animal groups. There is a significant increase in [HbO2] among DHCPB animals that is well above baseline values (P = .019), indicating potential overdelivery of oxygen. There is a trend toward increased THC in DHCPB animals as well, but this does not reach significance (P = .070). CPB, Cardiopulmonary bypass; DHCPB, deep hypothermic cardiopulmonary bypass; DHCA, deep hypothermic circulatory arrest; SACP, selective antegrade cerebral perfusion.