TABLE 2.
The correlation between NCAPG and gene markers of immune cells examined by TIMER database.
| Description | Gene markers | LUAD | |||
|---|---|---|---|---|---|
| None | Purity | ||||
| Cor | p | Cor | p | ||
| B cell | CD19 | 0.501 | *** | 0.347 | *** |
| — | CD79A | 0.415 | *** | 0.275 | *** |
| T cell (general) | CD3D | 0.65 | *** | 0.633 | *** |
| — | CD3E | 0.718 | *** | 0.543 | *** |
| — | CD2 | 0.736 | *** | 0.654 | *** |
| CD8+ T cell | CD8A | 0.551 | *** | 0.445 | *** |
| — | CD8B | 0.444 | *** | 0.348 | *** |
| Monocyte | CD86 | 0.581 | *** | 0.475 | *** |
| — | CSF1R | 0.62 | *** | 0.533 | *** |
| TAM | CCL2 | 0.382 | *** | 0.265 | *** |
| — | CD68 | 0.436 | *** | 0.335 | *** |
| — | IL10 | 0.449 | *** | 0.328 | *** |
| M1 | IRF5 | 0.55 | *** | 0.482 | *** |
| M2 | CD163 | 0.449 | *** | 0.342 | *** |
| — | VSIG4 | 0.397 | *** | 0.304 | *** |
| — | MS4A4A | 0.425 | *** | 0.304 | *** |
| Neutrophils | CEACAM8 | 0.202 | *** | 0.196 | *** |
| — | ITGAM | 0.602 | *** | 0.523 | *** |
| — | CCR7 | 0.704 | *** | 0.622 | *** |
| Natural killer cell | KIR2DL1 | 0.173 | *** | 0.109 | *** |
| — | KIR2DL3 | 0.239 | *** | 0.163 | *** |
| — | KIR2DL4 | 0.261 | *** | 0.178 | *** |
| — | KIR3DL1 | 0.207 | *** | 0.136 | *** |
| — | KIR3DL2 | 0.295 | *** | 0.22 | *** |
| — | KIR2DS4 | 0.209 | *** | 0.134 | *** |
| Dendritic cell | HLA-DPB1 | 0.621 | *** | 0.54 | *** |
| — | HLA-DQB1 | 0.486 | *** | 0.391 | *** |
| — | HLA-DRA | 0.567 | *** | 0.472 | *** |
| — | HLA-DPA1 | 0.602 | *** | 0.527 | *** |
| — | CD1C | 0.46 | *** | 0.385 | *** |
| — | NRP1 | 0.267 | *** | 0.238 | *** |
| — | ITGAX | 0.644 | *** | 0.559 | *** |
| Th1 | TBX21 | 0.689 | *** | 0.628 | *** |
| — | STAT4 | 0.615 | *** | 0.51 | *** |
| — | STAT1 | 0.474 | *** | 0.385 | *** |
| — | TNF | 0.549 | *** | 0.448 | *** |
| — | IFNG | 0.486 | *** | 0.4 | *** |
| Th1-like | HAVCR2 | 0.578 | *** | 0.468 | *** |
| — | CXCR3 | 0.696 | *** | 0.62 | *** |
| — | BHLHE40 | 0.235 | *** | 0.204 | *** |
| — | CD4 | 0.673 | *** | 0.582 | *** |
| Th2 | STAT6 | 0.287 | *** | 0.337 | *** |
| — | STAT5A | 0.671 | *** | 0.597 | *** |
| Treg | FOXP3 | 0.725 | *** | 0.648 | *** |
| — | CCR8 | 0.658 | *** | 0.578 | *** |
| — | TGFB1 | 0.287 | *** | 0.409 | *** |
| Effector Treg T cells | TNFRSF9 | 0.684 | *** | 0.576 | *** |
| — | FGFBP2 | 0.182 | *** | 0.114 | *** |
| — | FCGR3A | 0.458 | *** | 0.35 | *** |
| Effector T cells | CCR7 | 0.704 | *** | 0.622 | *** |
| — | SELL | 0.662 | *** | 0.568 | *** |
| Naive T cells | GZMK | 0.618 | *** | 0.519 | *** |
| — | CD69 | 0.569 | *** | 0.47 | *** |
| Effector memory T cells | CXCR6 | 0.624 | *** | 0.52 | *** |
| — | MYADM | 0.314 | *** | 0.227 | *** |
| Resident memory T cells | IL7R | 0.584 | *** | 0.475 | *** |
| — | HAVCR2 | 0.578 | *** | 0.468 | *** |
| — | LAG3 | 0.551 | *** | 0.469 | *** |
| — | CXCL13 | 0.502 | *** | 0.371 | *** |
| Memory T cells | LAYN | 0.336 | *** | 0.2 | *** |
*p < 0.05, **p < 0.01, ***p < 0.001.