TABLE 5.
Univariate GEE model for patients with ST-segment elevation myocardial infarction (STEMI) with the full dataset for mortality.
| Predictors | OR (95% CI) | p | QIC | AUC | Cut-off | Sensitivity | Specificity |
| Clinical Parameters | |||||||
| Age (years) | 1.105(1.036,1.179) | 0.002 | 292.756 | 0.829(0.819,0.838) | > 74.500 | 0.679 | 0.871 |
| Heart rate (bpm) | 1.03(1.001,1.061) | 0.04 | 337.404 | 0.687(0.677,0.697) | > 76.000 | 0.836 | 0.614 |
| SBP (mmHg) | 0.962(0.944,0.98) | < 0.01 | 302.870 | 0.742(0.682,0.802) | < 99.500 | 0.941 | 0.437 |
| Emergency PCI, n(%) | 0.354(0.134,0.937) | 0.04 | 339.008 | 0.606(0.535,0.676) | – | – | – |
| IABP or ECMO use | 6.059(1.587,23.13) | 0.01 | 324.813 | 0.631(0.618,0.644) | – | – | – |
| LVEF (%) | 0.889(0.831,0.952) | <0.01 | 321.085 | 0.644(0.575,0.713) | < 49.500 | 0.500 | 0.742 |
| Neutrophils% | 1.06(1.013,1.111) | 0.01 | 329.642 | 0.688(0.679,0.698) | > 74.750 | 0.660 | 0.673 |
| TC(mmol/l) | 1.572(1.025,2.412) | 0.04 | 339.157 | 0.62(0.605,0.634) | > 3.715 | 0.833 | 0.478 |
| Metabolites | |||||||
| L-Threonine | 1.016(1.012,1.021) | < 0.01 | 199.31 | 0.915(0.862–0.964) | 6760000 | 0.708 | 0.979 |
| 3-Methyl-2-butene-1-thiol | 1.012(1.009,1.016) | < 0.01 | 253.04 | 0.859(0.768–0.922) | 5780000 | 0.625 | 0.979 |
| N-Acetyl-leukotriene E4 | 0.880(0.851,0.909) | < 0.01 | 149.20 | 0.952(0.909–0.98) | 501000 | 0.979 | 0.792 |
| LysoPC(18:0) | 0.991(0.989,0.993) | < 0.01 | 145.35 | 0.957(0.921–0.983) | 17900000 | 0.98 | 0.8 |
| Dehydrophytosphingosine | 1.101(1.063,1.14) | < 0.01 | 204.36 | 0.927(0.873–0.969) | 270000 | 0.729 | 0.979 |
| 4-Hydroxy-6-docosanone(*105) | 0.808(0.765,0.852) | < 0.01 | 202.37 | 0.889(0.829–0.943) | 535000 | 0.667 | 0.979 |
| 9-cis-Retinoic acid(*104) | 1.065(1.022,1.110) | < 0.01 | 306.59 | 0.956(0.916–0.985) | 101.865 | 0.875 | 0.875 |
AUC, area under the curve; ECMO, extracorporeal membrane oxygenation; GEE, generalized estimating equation; IABP, intra-aortic balloon pump; LVEF, left ventricular ejection fraction; LysoPC, lysophosphatidylcholine; OR, odds ratio; PCI, percutaneous coronary intervention; QIC, quasi-likelihood under the independence model criterion; SBP, systolic pressure; TC, total cholesterol.