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TABLE 3.

Evaluation of three serologic assays for the detection of H5-specific antibody in confirmed and suspected H5N1 virus-infected individuals and nonexposed controls

Age group Serum Sample H5-specific antibody response
Na ELISAb
WBa
IgG IgM
Children
B S1 10 5.6 5.6
S2 80 16.6 5.6 +d
F S2 14 14.6 16.6 +d
G S1 10 5.6 8.6
S2 320 14.6 14.6 +d
H S1 10 5.6 5.6 NTe
S2 450 18.6 16.6 +
Control (n = 24) 11 6.0 5.6
Adults
A S1 20 18.6 5.6 +
S2 160 18.6 5.6 +
D S1 10 6.6 6.6
S2 320 18.6 18.6 +d
I S1 10 5.6 5.6
S2 1,280 18.6 18.6 +
J S2 10 5.6 5.6
Control (n = 46) 20 11.0 6.0
a

N, microneutralization assay; GMT to A/Hong Kong/156/97 virus. 

b

GMT (log2). 

c

W, Western blotting. +, positive; −, negative. 

d

Serum also positive with IgM. 

e

NT, not tested.