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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Br J Pharmacol. 2021 Aug 12;178(22):4468–4484. doi: 10.1111/bph.15623

Figure 4: Glomerular injury in experimental groups.

Figure 4:

Calculated values of glomerular injury score (A) and glomerular nephrin expression (C) at the end of the 8-week experimental protocol. Representative photomicrograph showing damaged glomeruli (arrows) (B) and nephrin expression (arrows) in the glomeruli of different experimental groups analyzed at the end of the protocol (D). *p<0.05 vs. lean ZSF1-Vehicle; ‡p<0.05 vs. obese ZSF1-Vehicle. ENAL = enalapril. Data are reported as box and whisker plots with median and minimum to maximum, n=6/group. Dual acting sEH-COX-2 inhibitor PTUPB attenuated angiotensin II (ANG II)-induced glomerular albumin permeability (E). *p<0.05 vs. Baseline; ‡p<0.05 vs. ANG II-PTUPB. All data expressed as mean ± SEM, n=10group