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[Preprint]. 2022 Feb 24:2022.02.18.481058. Originally published 2022 Feb 18. [Version 2] doi: 10.1101/2022.02.18.481058

Fig. 1. F6 binds to prevalent RBD mutants and neutralizes SARS-CoV-2 VOCs including Omicron.

Fig. 1.

A. Heat map of VH F6 binding to circulating RBD mutants. The binding of VH F6 to RBD mutants was detected by ELISA and normalized by comparing area under the curves (AUCs) between mutant and wild type RBD. B. Neutralization of SARS-CoV-2 WT, Alpha, Beta, Gamma, Delta, and Omicron variants pseudovirus by VH F6. Experiments were performed in duplicate and error bars denote ± SD, n=2. C. Measurement of VH F6 binding to the Omicron RBD by ELISA (left) and BlitZ (right).