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. Author manuscript; available in PMC: 2022 Feb 28.
Published in final edited form as: Oncogene. 2021 Aug 31;40(42):6071–6080. doi: 10.1038/s41388-021-01994-0

Figure 3. Influence of PHF10 knockdown on MYC-PBAF interaction in A375 cells.

Figure 3.

(A) Knockdown of PHF10 significantly decreases its intracellular abundance. (B) PHF10 knockdown does not disrupt PBAF complexes. Immunoprecipitation with antibodies against different PBAF subunits (indicated on top) from the wild type (siPHF10−) and PHF10 knockdown (siPHF10+) cells. (C) Co-immunoprecipitation of MYC with antibodies against BAF200 and BAF155 subunits or with control IgG from extracts of the wild type and PHF10 knockdown cells. Note that the knockdown significantly reduces the amounts of MYC co-precipitated with PBAF.