Table 2.

The effect of T2-abnormalities in the MCP and globus pallidus on FXTAS clinical symptoms in premutation carriers.

Comparisons	OR/β	95% CI	P	FDR
Intention tremor (N = 170)
MCP (odds ratio)	16.0	(2.12, 120.6)	0.007*	0.012
Cerebellar ataxia (N = 170)
MCP (odds ratio)	3.64E + 07	(7.7E + 05, 1.7E + 10)	<0.001*	<0.001
BDS (N = 166)
Pallidus	1.41	(−0.72, 3.54)	0.20	0.20
MCP	−2.90	(−4.30, −1.49)	<0.001*	<0.001
MCP-by-pallidus	−3.04	(−5.86, −0.22)	0.036*	0.045

^*Significant at FDR 0.05.

OR, odds ratio; CI, confidence interval; FDR, false discovery rate; MCP, middle cerebellar peduncle.