Table 1. Selected quantitative measures of acceptability and preference.

Domain	Measure*	Response options	Timepoint
Acceptability	Overall, how much do you like the ring?	10-point Likert scale	Day 28 & Day 91/PUEV
		1 = Extremely Dislike, 5 = Neutral, 10 = Extremely Like
	How do you like the ring now compared to when you started the study?	I like it MORE now,	Day 28 & Day 91/PUEV
		I like it LESS now,
		I like it the SAME,
		I do not like the ring
	How did it feel to have the ring inside you every day?	Very comfortable, comfortable,	Day 28 & Day 91/PUEV
		uncomfortable, very uncomfortable
	How easy or difficult was it to use the ring?	Very difficult, difficult, easy, very easy	Day 28 & Day 91/PUEV
	Were you aware of the ring during your normal daily activities?	Never, some of the time, most of the time, all of the time	Day 28 & Day 91/PUEV
	Have you noticed any of the following changes in your vagina while wearing the ring?  • Vagina was wetter  • Vagina was drier  • Your vagina had a change in odor or scent	Yes, no	Day 28 & Day 91/PUEV
		Not at all, a little, somewhat, very much
	How much has the change bothered you?
	How worried are you about the ring being dirty or unhygienic?	Not at all, a little, somewhat, very much	Day 28 & Day 91/PUEV
	How worried are you about the ring causing infection, infertility, or other long term health problems?	Not at all, a little, somewhat, very much	Day 28 & Day 91/PUEV
	How much did it bother you to wear the ring during menses?	10-point Likert scale	Day 28 & Day 91/PUEV
		1 = Not at all,10 = Very much
	How often did you feel the ring inside you when you had sex?	Never, some of the time, most of the time, all of the time,	Day 28 & Day 91/PUEV
	How much did it bother you?	I never had sex with the ring in
		Not at all, a little, somewhat, very much
Preferences	Which would you prefer: a ring that can be worn for three months and then replaced with a new one, or one that must be replaced with a new one every month?	Prefer 3 months,	Day 91/PUEV
		Prefer 1 month,
		No preference
	Which would you prefer: a ring that you leave in continuously, or a ring that you insert only on the days when you have sex?	Prefer leaving in continuously,	Day 91/PUEV
		Prefer inserting only when I have sex,
		No preference
	Which do you think your primary partner would prefer as a method to prevent HIV?	Ring,	Day 91/PUEV
		Condom,
		PrEP (daily oral pill),
		Don’t know,
		N/A—no partner

* all questions were asked in relation to the time period since the start of the study