Table 1. Significant overlaps between DEG sets.
| Overlaps within brain regions | Overlaps between brain regions | ||
|---|---|---|---|
| DEG set 1/DEG set 2 | overlap p value | DEG set 1/DEG set 2 | overlap p value |
| AP1vE18-down/AP3vE18-down | 6.4E-95 | AP1vE18-down/SP3vE18-down | 4.9E-13 |
| AP1vE18-down/AP3vP1-up | 8.5E-08 | AP1vE18-down/SP1vE18-down | 2.0E-08 |
| AP1vE18-up/AP3vP1-down | 1.8E-81 | AP1vE18-down/HP1vE18-down | 4.1E-08 |
| AP1vE18-up/AP3vE18-up | 9.9E-26 | AP1vE18-up/FCP3vP1-down | 7.8E-65 |
| AP3vE18-down/AP1vE18-down | 6.4E-95 | AP1vE18-up/FCP1vE18-up | 1.6E-51 |
| AP3vE18-down/AP3vP1-down | 6.9E-51 | AP1vE18-up/SP3vE18-up | 1.0E-15 |
| AP3vE18-up/AP1vE18-up | 9.9E-26 | AP3vE18-down/HP3vE18-down | 3.1E-35 |
| AP3vE18-up/AP3vP1-up | 9.4E-08 | AP3vE18-down/SP3vP1-down | 2.6E-26 |
| FCP1vE18-down/FCP3vE18-down | 1.2E-43 | AP3vE18-down/SP3vE18-down | 2.3E-24 |
| FCP1vE18-down/FCP3vP1-up | 7.5E-11 | AP3vE18-up/HP3vE18-up | 1.0E-139 |
| FCP1vE18-up/FCP3vP1-down | 3.8E-65 | AP3vE18-up/HP1vE18-up | 6.1E-49 |
| FCP3vE18-down/FCP1vE18-down | 1.2E-43 | AP3vE18-up/SP3vE18-up | 1.1E-25 |
| FCP3vE18-down/FCP3vP1-down | 4.9E-18 | AP3vP1-down/FCP3vP1-down | 1.1E-58 |
| FCP3vE18-up/FCP3vP1-up | 1.1E-12 | AP3vP1-down/FCP1vE18-up | 8.5E-49 |
| SP1vE18-down/SP3vE18-down | 2.6E-35 | AP3vP1-down/SP3vP1-down | 4.7E-14 |
| SP1vE18-down/SP3vP1-up | 5.7E-08 | AP3vP1-up/FCP3vP1-up | 2.6E-15 |
| SP3vE18-down/SP3vP1-down | 5.9E-34 | AP3vP1-up/SP3vP1-up | 7.6E-12 |
| SP3vE18-up/SP3vP1-up | 2.5E-48 | FCP1vE18-down/SP1vE18-down | 9.0E-10 |
| HP1vE18-down/HP3vE18-down | 3.6E-30 | FCP1vE18-down/SP3vE18-down | 1.3E-09 |
| HP1vE18-up/HP3vE18-up | 2.2E-68 | FCP1vE18-up/HP1vE18-down | 1.9E-08 |
| FCP3vE18-up/HP3vE18-up | 2.4E-35 | ||
| FCP3vE18-up/SP3vE18-up | 5.4E-19 | ||
| FCP3vE18-up/SP3vP1-up | 7.0E-16 | ||
| SP3vE18-up/HP3vE18-up | 1.6E-61 | ||
| SP3vP1-down/HP3vE18-down | 2.4E-18 | ||
| SP3vP1-up/HP3vE18-up | 1.8E-52 | ||
Each DEG set was compared against each other to identify significant overlaps and assign p values using a hypergeometric test. Numbers of genes in each overlap are shown in Figs 2B; only overlaps of at least 3 genes were considered. Where more than 3 overlapping DEG sets with p < 0.05 were identified for each set the top three are listed; otherwise all non-redundant, significant overlaps are shown. A full list is included in S2 Table.