Table 1.
List of some of commonly observed mutated strains of SARS-CoV-2 and their mutation in the receptor binding domain.
| Commonly observed variants | Pango Lineage | Mutations in the receptor binding domain (RBD) in the surface glycoprotein |
|---|---|---|
| Alpha | B.1.1.7 | E484K, S494P, N501Y |
| Beta | B.1.351, B.1.351.2, B.1.351.3 | K417N, E484K, N501Y |
| Gamma | P.1, P.1.1, P.1.2 | K417N, E484K, N501Y |
| Delta | B.1.617.2, AY.1, AY.2, AY.3 | K417N, L452R, T478K |
| Omicron | B.1.1.529 | G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H |
| Lambda | C.37 | L452Q, F490S |
| Mu | B.1.621 | R346K, E484K, N501Y |
| Kappa | B.1.617.1 | L452R, E484Q |
| Eta | B.1.525 | E484K |
| Iota | B.1.526 | L452R, S477N, E484K |
| Epsilon | B.1.427, B.1.429 | L452R |
| Zeta | P.2 | E484K |
| _ | B.1.1.519 | T478K |
| _ | B.1.620 | S477N, E484K |
| _ | B.1.177 | T445C |
| _ | B.1.617.3 | L452R, E484Q |