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. 2022 Feb 14;29(1):519–533. doi: 10.1080/10717544.2022.2032876

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — In vitro dual-modal imaging. (A) Photoacoustic images of FA-DOX-ICG-PFP@Lip (0.625, 1.25, 2.5, and 5 mg/mL), DOX-ICG-PFP@Lip (5 mg/mL), and saline. (B) Photoacoustic values of FA-DOX-ICG-PFP@Lip (0.625, 1.25, 2.5, and 5 mg/mL). (C) Photoacoustic values of FA-DOX-ICG-PFP@Lip (5 mg/mL), DOX-ICG-PFP@Lip (5 mg/mL), and saline. (D) B-mode and (E) contrast-enhanced ultrasound images of FA-DOX-ICG-PFP@Lip (0.625, 1.25, 2.5, and 5 mg/mL), DOX-ICG-PFP@Lip (5 mg/mL), and saline with laser irradiation at 1 W/cm² for 5 min. (F) Echo intensity of FA-DOX-ICG-PFP@Lip (0.625, 1.25, 2.5, and 5 mg/mL) in B-mode and contrast-enhanced ultrasound. (G) Echo intensities of FA-DOX-ICG-PFP@Lip (5 mg/mL), DOX-ICG-PFP@Lip (5 mg/mL), and saline (**p<.01).