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. 2022 Feb 14;29(1):519–533. doi: 10.1080/10717544.2022.2032876

Figure 4.

Figure 4.

Cytotoxicity, in vitro cellular uptake, and anticancer effects of liposomes. (A) Cytotoxicity against HUVEC and Y79 cells after incubation with FA-ICG-PFP@Lip (DOX-free) for 24 hours. (B) Confocal laser scanning micrographs images of Y79 cells after different treatments (nontargeted group: DOX-ICG-PFP@Lip, targeted group: FA-DOX-ICG-PFP@Lip, and antibody antagonist group: free folic acid + FA-DOX-ICG-PFP@Lip). (C) Anticancer efficacy of different therapies against Y79 cells (control, laser only, DOX only, FA-DOX-ICG-PFP@Lip, FA-ICG-PFP@Lip + laser, DOX-ICG-PFP@Lip + laser, FA-DOX-ICG-PFP@Lip + laser) (**p<.01).